Stem Cell Therapy in Duchenne Muscular Dystrophy

Stem Cell Therapy in Duchenne Muscular Dystrophy


Duchenne Muscular Dystrophy (DMD) is an X-linked recessive genetic disease. Worldwide, around 1 in 3500 boys suffer from DMD. The child is usually normal at birth but the disease onsets around 3 years of age. Initially, the child starts feeling difficulty in getting up from the ground which is accompanied by frequent falling on brisk walking. Gradually, the problem going on increasing in the form of calf muscle enlargement with inability to climb the staircase. In the following time, all the muscles of the body starts to lose power and the child is bed-ridden between the age of 8-10 years. In most cases, death occurs between 14 to 21 years due to respiratory or cardiac failure. DMD results due to deficiency of a protein called dystrophin in the muscle cells.Stem Cell Based Therapies for Duchenne Muscular Dystrophy


However, Stem Cell Treatment for Duchenne Muscular Dystrophy now offers hope. Like any other degenerative disorders, DMD is the result of the loss of cells which are required for the proper functioning of the body. In the case of DMD, a vital muscle protein is mutated, and its absence results in progressive degeneration of essentially all of the muscles in the body.